Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5220984 | Tetrahedron | 2011 | 8 Pages |
Abstract
A novel synthesis of highly fused perimidine derivatives was achieved in two steps from 2-alkynylbenzaldehydes. Copper-catalyzed annulation of 2-[(2-bromophenyl)ethynyl]benzaldehydes with 1,8-diaminonaphthalene produced dihydroisoquinolino[2,1-a]perimidines bearing a 2-bromophenyl group. Subsequent palladium-catalyzed C-H arylation provided dibenzo[1,2:7,8]quinolizino[3,4,5,6-kla]perimidine derivatives in moderate to good yields.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yusuke Tokimizu, Yusuke Ohta, Hiroaki Chiba, Shinya Oishi, Nobutaka Fujii, Hiroaki Ohno,