Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5221019 | Tetrahedron | 2012 | 5 Pages |
Abstract
By a combination of cyclodehydration of N-acyl amino acids with N,Nâ²-diisopropylcarbodiimide (DIC) and non-classical Wittig olefination of the resultant 5(4H)-oxazolones with Ph3PCHCN and Ph3PCHCOOEt, 5-oxazoleacetonitriles and 5-oxazoleacetates were synthesized in one-pot in 41-85% and 57-70% yields, respectively.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Wenhua Huang, Guangping Dong, Zumureti Mijiti,