Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5221096 | Tetrahedron | 2010 | 5 Pages |
Abstract
Different outcomes were generated under different conditions for the three-component reaction of Nâ²-(2-alkynylbenzylidene)hydrazide, α,β-unsaturated carbonyl compound, with bromine. 6-BromoH-pyrazolo[5,1-a]isoquinoline was obtained when the reaction was performed in NMP at 70 °C in the presence of DABCO as base, while 6-bromo-1,2,3,10b-tetrahydropyrazolo[5,1-a]isoquinoline was afforded when the reaction occurred in DMAc at 10 °C in the presence of K3PO4 as the base.
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Related Topics
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Organic Chemistry
Authors
Hui Ren, Shengqing Ye, Fen Liu, Jie Wu,