Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5221161 | Tetrahedron | 2012 | 6 Pages |
Abstract
Conditions have been developed for the regioselective synthesis of 4-substituted isoxazoles from terminal alkynes and 3,4-disubstituted isoxazoles from internal alkynes. The methodology involves a one-pot titanium-catalyzed multicomponent coupling reaction followed by simple hydroxylamine hydrochloride addition.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Amila A. Dissanayake, Aaron L. Odom,