| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5221170 | Tetrahedron | 2012 | 6 Pages |
Abstract
A convenient synthetic pathway to novel functionalized tetrapeptides containing the 1,2,3-triazole moiety is described. The target molecules were obtained by the reaction of fluorinated α-amino acids or α-aminophosphonates with azidopeptides via Cu(I)-catalyzed Huisgen cycloaddition reaction (click chemistry). The synthesized tetrapeptides may find important applications in biomedical chemistry as potential drugs.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Daria V. Vorobyeva, Nadezhda V. Sokolova, Valentine G. Nenajdenko, Alexander S. Peregudov, Sergey N. Osipov,