Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5221175 | Tetrahedron | 2012 | 7 Pages |
Abstract
A transition metal-free tandem process for the synthesis of pyrrolopyrazino[2,3-d]pyridazine-diones is described. The process is an efficient construction of this tricyclic system by a one-pot coupling/Smiles rearrangement/cyclization approach. This methodology has potential applications in the synthesis of biologically and medicinally relevant compounds.
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