| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5221313 | Tetrahedron | 2012 | 10 Pages |
Abstract
The preparation of 6-aminoquinazolin-4(3H)-ones requires the use of platinum-metal group catalysis on the corresponding C-6-iodo or 6-bromo precursors. Herein, we report to our knowledge the first successful SNAr reaction directly at the unactivated C-6 position of the quinazolin-4(3H)-one nucleus.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Bernard Barlaam, Craig S. Harris, Jonathan Lecoq, Ha Thi Hoang Nguyen,