Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5221318 | Tetrahedron | 2012 | 7 Pages |
Abstract
An efficient sodium bicarbonate promoted aerobic oxidation reaction to prepare N-monosubstituted α-keto amides in the presence of n-tetrabutylammonium hydrogensulfate (TBAHS) was described. This reaction provides a very simple and convenient synthetic route to N-monosubstituted α-keto amides from easily available aryl- or heteroarylacetamides in good to high yields without using toxic reagents and harsh conditions.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jun Shao, Xiaomei Huang, Siyuan Wang, Bingxin Liu, Bin Xu,