Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5221343 | Tetrahedron | 2012 | 7 Pages |
Abstract
Nine linear polyoxygenated acetylenes, fulvynes A–I (1–9), exhibiting the uncommon 2-yne carboxylic acid functionality, have been isolated from the butanolic extract of the Mediterranean sponge Haliclona fulva. Their structures possess a long alkyl chain with several oxygenated carbons, and were established by detailed spectroscopic analysis. All fulvynes were found to be active against a chloramphenicol-resistant strain of Bacillus subtilis.
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