Article ID Journal Published Year Pages File Type
5221388 Tetrahedron 2010 7 Pages PDF
Abstract

A tandem dienyne metathesis based strategy has been developed for construction of the core tricyclic framework found in the lepadiformine and cylindricine alkaloids. 2-Pentenyl-2-ethynylpyrollidine acrylamide that serves as the starting material for the key ruthenium carbene catalyzed metathesis process is prepared by using a concise route starting with l-proline.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry