Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5221388 | Tetrahedron | 2010 | 7 Pages |
Abstract
A tandem dienyne metathesis based strategy has been developed for construction of the core tricyclic framework found in the lepadiformine and cylindricine alkaloids. 2-Pentenyl-2-ethynylpyrollidine acrylamide that serves as the starting material for the key ruthenium carbene catalyzed metathesis process is prepared by using a concise route starting with l-proline.
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