| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5221437 | Tetrahedron | 2011 | 5 Pages |
Abstract
We have successfully obtained the first unambiguous spectroscopic proof of the structure of heptafluoropropan-2-ol by 13C NMR, which has been assumed from early 70s but without unequivocal evidence. Equilibrating relationship between fluorinated ketones and the corresponding hydrates as well as α-fluoroalcohols in anhydrous HF was at least qualitatively supported by our ab initio computation, and moreover, anhydrous HF as a convenient solvent was found to offer an effective new route for production of 1,1,1,3,3,3-hexafluoropropan-2-ol in industrial scales.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
