Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5221473 | Tetrahedron | 2010 | 6 Pages |
Abstract
A new method for the synthesis of 3-halo-6-(N-tosyl-2-pyrrolyl)pyridazine 7 was developed. Suzuki cross-coupling reactions of 7 with arylboronic acids and in situ de-tosylation gave a variety of novel 3-aryl-6-(2-pyrrolyl)pyridazines. It found that protection of the pyrrolyl moiety was necessary for efficient coupling reaction.
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