| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5221487 | Tetrahedron | 2010 | 6 Pages |
Abstract
New trifunctional organocatalysts with a NHTs Brønsted acid were prepared and tested in their ability to promote the counterion catalysis of generic and aza-Morita/Baylis/Hillman reactions. The cooperativity between the counterion and the NHTs Brønsted acid of the trifunctional catalyst was required for good enantioselectivity and rate enhancement. Better enantioselectivity was observed for aza-MBH reactions at relatively low catalyst loading (2-5 mol %) under facile conditions.
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Authors
Christopher Anstiss, Fei Liu,