Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5221681 | Tetrahedron | 2011 | 7 Pages |
Abstract
Six new cyclohexadepsipeptides, beauvenniatins A-E (1-5), and beauvericin J (6), together with the known beauvericin (7) and enniatin B (8), were isolated from the fungus Acremonium sp. BCC 28424. The productions of minor derivatives 3-6, possessing an N-methyl-l-tyrosine, were enhanced by feeding l-tyrosine in the liquid fermentation medium. Antimalarial, antitubercular, and cytotoxic activities of these cyclodepsipeptides were evaluated.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Masahiko Isaka, Arunrat Yangchum, Malipan Sappan, Rapheephat Suvannakad, Prasert Srikitikulchai,