| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5221685 | Tetrahedron | 2011 | 8 Pages |
Abstract
An efficient formal synthesis of racemic valiolamine starting from readily available myo-inositol is reported. In all the synthetic steps only one regioisomer is formed, which circumvents laborious purification of products. Regioselective benzylation of myo-inositol orthoformate, super-hydride mediated deoxygenation of a cyclitol derivative and stereoselective addition of dichloromethyllithium to an inosose are the key reactions in the synthesis.
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Related Topics
Physical Sciences and Engineering
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Organic Chemistry
