| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5221689 | Tetrahedron | 2011 | 11 Pages |
Abstract
A new enantioselective synthesis of ABEF ring analogues of methyllycaconitine has been developed using a chiral cobalt(III) salen-catalyzed Diels-Alder reaction to form the B ring. Subsequent elaboration to form the A, E and F rings was achieved by sequential Dieckmann, Mannich and Wacker-type cyclizations to afford tetracyclic analogues in 97.5% ee.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kevin Sparrow, David Barker, Margaret A. Brimble,