Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5221742 | Tetrahedron | 2011 | 7 Pages |
Abstract
The reaction of chromone-derived Morita–Baylis–Hillman acetates with amines was developed via tandem allylic amination/chromone ring-opening/oxa-Michael addition to provide 2-substituted-3-aminomethy-lene-chromans in convenient and efficient way, and subsequent applied in the synthesis of benzopyranylpyrimidine compounds. Various amines exhibited different reactivities depending on their molecular structural characteristics.
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