Article ID Journal Published Year Pages File Type
5221742 Tetrahedron 2011 7 Pages PDF
Abstract

The reaction of chromone-derived Morita–Baylis–Hillman acetates with amines was developed via tandem allylic amination/chromone ring-opening/oxa-Michael addition to provide 2-substituted-3-aminomethy-lene-chromans in convenient and efficient way, and subsequent applied in the synthesis of benzopyranylpyrimidine compounds. Various amines exhibited different reactivities depending on their molecular structural characteristics.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry