Article ID Journal Published Year Pages File Type
5221751 Tetrahedron 2011 4 Pages PDF
Abstract

A rapid and convenient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2-ones and thiones was developed. The reaction involves a one-pot reaction between oxalacetic acid, thiourea/urea, and aldehyde under microwave irradiation and provides the products in good yields and much shorter reaction times.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry