| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5221772 | Tetrahedron | 2010 | 5 Pages |
Abstract
Ferric chloride (FeCl3) promoted electron transfer oxidation of bicyclic cyclopropyl silyl ethers was performed in biphasic solution system of 1-butyl-3-methylimidazolium hexafluorophosphate (BmimPF6) and benzotrifluoride (BTF). The resulting chloro-substituted ring-expanded cycloalkanones were treated with an appropriate base to produce substituted cyclic enones. These two-step reactions were successfully devised to proceed in a simpler manner in which the ordinary work-up operations for the former oxidation step, such as water-quench, extraction, and evaporation, were omitted; imidazole was found to be the most suitable base for the latter elimination step.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hiroyuki Tsuchida, Eietsu Hasegawa,