| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5221802 | Tetrahedron | 2011 | 6 Pages |
Abstract
The nucleophilic fluorination of 1,2,2-triaryl-2-hydroxyethanones by fluoride ion has been carried out using pyridinium poly(hydrogen fluoride) (PPHF) to give 1,2,2-triaryl-2-fluoroethanones in fairly good yield. The presence of electron withdrawing group (EWG), such as -COAr at the carbon bearing hydroxyl group facilitates such nucleophilic fluorination. The intermediacy of bridged oxiranyl ion and α-ketocarbenium ion has been proposed for the formation of various α-fluoroketones and benzofuran derivatives respectively.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Anil Kumar, Anil K. Pal, Rishi D. Anand, Tej V. Singh, Paloth Venugopalan,