| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5221897 | Tetrahedron | 2011 | 7 Pages |
Abstract
A short convergent synthesis of the fungal metabolites cephalosporolides E and F is reported. The key step makes use of a chelation-controlled Mukaiyama aldol reaction to access the key acyclic spiroacetal precursor with the required syn stereochemistry.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![A convergent synthesis of the [4.4]-spiroacetal-γ-lactones cephalosporolides E and F](/preview/png/5221897.png "First Page Preview: A convergent synthesis of the [4.4]-spiroacetal-γ-lactones cephalosporolides E and F")
Authors
Margaret A. Brimble, Orla C. Finch, Amanda M. Heapy, John D. Fraser, Daniel P. Furkert, Patrick D. O'Connor,