Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5221925 | Tetrahedron | 2010 | 10 Pages |
Abstract
An efficient and highly stereoselective asymmetric synthesis of C1-C9 and C9-C17 fragments of (+)-13-deoxytedanolide have been achieved. Utilization of desymmetrization technique to prepare the triol with five stereogenic centers, regioselective Sharpless asymmetric dihydroxylation, Evans' aldol reaction, chiral methylation, and Wittig olefination are highlights of the synthesis.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
J.S. Yadav, N. Rami Reddy,