Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5221967 | Tetrahedron | 2011 | 4 Pages |
Abstract
A facile and efficient approach to a variety of 6-chloro-3,5-disubstituted 3H-pyrimidin-4-ones 2/6 from the readily available cyanoacetamides 1/5 under Vilsmeier conditions was developed, in which the Vilsmeier reagent plays multiple roles and the possible mechanism is discussed.
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