Article ID Journal Published Year Pages File Type
5221967 Tetrahedron 2011 4 Pages PDF
Abstract

A facile and efficient approach to a variety of 6-chloro-3,5-disubstituted 3H-pyrimidin-4-ones 2/6 from the readily available cyanoacetamides 1/5 under Vilsmeier conditions was developed, in which the Vilsmeier reagent plays multiple roles and the possible mechanism is discussed.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry