Article ID Journal Published Year Pages File Type
5222002 Tetrahedron 2009 14 Pages PDF
Abstract

Dialdehydes undergo 'radical then aldol' cyclization cascades upon treatment with SmI2, generating four contiguous stereocenters with high diastereocontrol. The scope of the process has been explored and the cascade has been extended to also include lactone reduction.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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