Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222002 | Tetrahedron | 2009 | 14 Pages |
Abstract
Dialdehydes undergo 'radical then aldol' cyclization cascades upon treatment with SmI2, generating four contiguous stereocenters with high diastereocontrol. The scope of the process has been explored and the cascade has been extended to also include lactone reduction.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Matthew D. Helm, Madeleine Da Silva, David Sucunza, Madeleine Helliwell, David J. Procter,