Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222070 | Tetrahedron | 2011 | 7 Pages |
Abstract
The synthesis of novel functionalized 3-amino-N-methylfuro[3,2-b]pyridine-2-carboxamides is described from cyanopyridine intermediates. Based on the difference in halogen reactivity, ethyl [(5-bromo-2-chloropyridin-3-yl)oxy]acetate was functionalized by a palladium-catalyzed reaction, before the cyclization to the desired furo[3,2-b]pyridines.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Anne Bretéché, Pascal Marchand, Marie-Renée Nourrisson, Patrick Hautefaye, Guillaume De Nanteuil, Muriel Duflos,