Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222106 | Tetrahedron | 2010 | 10 Pages |
Abstract
Enantiospecific synthesis of ABC-ring systems of A-nor and abeo 4(3â2) tetra and pentacyclic triterpenes has been accomplished starting from the readily available monoterpene (R)-carvone. (R)-Carvone was used as the B-ring of the target molecules. A lithium-liquid ammonia mediated cyclisation of δ,É-unsaturated ester was employed for the cyclopentannulation at the C-5 and C-6 carbons of carvone and an RCM reaction was employed for the cyclohexannulation to generate the ABC-ring system of A-nor tetra and pentacyclic triterpenes. The strategy has been extended for the synthesis of the ABC-ring system of abeo 4(3â2) tetra and pentacyclic triterpenes.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
A. Srikrishna, R. Ramesh Babu, B. Beeraiah,