| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5222122 | Tetrahedron | 2010 | 7 Pages |
Abstract
Synthesis of novel pyrroloisoquinoline and indolizinoindole derivatives with β-lactam unit has been achieved by sequential intermolecular 1,3-dipolar cycloaddition reaction and Pictet-Spengler cyclization. The azomethine ylide derived from β-lactam imine of α-amino ester in the presence of silver acetate reacted with nitrostyrenes to give pyrrolidinyl β-lactam, which underwent Pictet-Spengler cyclization in presence of trifluoroacetic acid to give pyrroloisoquinolines and indolizinoindoles.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Natarajan Arumugam, Raghavachary Raghunathan,