Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222146 | Tetrahedron | 2009 | 7 Pages |
Abstract
19-Norvitamin D analogs 3a and 3b were synthesized from 25-hydroxyvitamin D, obtained via a bioconversion method. The synthetic route features a highly regio- and stereoselective hydroboration reaction to afford 25-hydroxy-3,5-cyclopropyl-vitamin D derivatives 12 having olefin at the C1-10-position.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Asako Toyoda, Hazuki Nagai, Tomonari Yamada, Yusuke Moriguchi, Junko Abe, Toshio Tsuchida, Kazuo Nagasawa,