Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222166 | Tetrahedron | 2011 | 6 Pages |
Abstract
A convenient and one-pot synthesis of 3-aroyl/heteroaroyl-2H-chromene-2-thiones and benzo[f]2H-chromene-2-thiones has been developed by the condensation of β-oxodithioesters and salicylaldehydes/α-hydroxynaphthaldehydes in the presence of indium trichloride under solvent-free conditions. The reaction is operationally facile, readily scalable, and offers rapid entry into differentially substituted chromene-2-thione scaffolds.
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