Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222183 | Tetrahedron | 2011 | 9 Pages |
Abstract
Microwave-assisted three-component reaction has been established for the regioselective synthesis of benzo[f]azulen-1-ones. The reaction was performed in aqueous media under microwave irradiation by using readily available and inexpensive starting materials. A total of 38 examples were examined to show a broad substrate scope and good overall yields (70-89%). The present new synthesis shows attractive green chemistry characteristics, such as the use of water as reaction media, concise one-pot conditions, short reaction periods (7-24Â min), easy work-up/purification, and reduced waste production without the use of any strong acids or metal promoters.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shu-Liang Wang, Chuang Cheng, Fei-Yue Wu, Bo Jiang, Feng Shi, Shu-Jiang Tu, Trideep Rajale, Guigen Li,