Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222184 | Tetrahedron | 2011 | 4 Pages |
Abstract
The superacid-promoted Houben/Hoesch reactions of amino-nitriles and related compounds have been studied. The nitriles form dicationic electrophiles and react with benzene in fair to good yields (12-95%). The intermediate iminium ions may also be reduced to the benzylic amines by NaBH4 or H2.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Erum K. Raja, Douglas A. Klumpp,