Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222187 | Tetrahedron | 2011 | 7 Pages |
Abstract
Enantioselective synthesis of 16-membered trilactone macrolides, macrosphelide A and E from (S)-lactic acid is described. Key features of the synthesis include the utility of a hitherto unexplored β-ketophosphonate derived from lactic acid and Yamaguchi lactonization leading to the title compounds.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kavirayani R. Prasad, Phaneendra Gutala,