Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222232 | Tetrahedron | 2009 | 7 Pages |
Abstract
An efficient entry into pyrazol-3-ones is described starting from propenoic acids that were first transformed into the corresponding hydrazides. Oxidation of the hydrazides gave the diazenes and the latter cyclized to pyrazol-3-ones on treatment with ZrCl4. The methoxycarbonyl protection of the N-1 of the pyrazolone derivatives was easily removed under mild reaction conditions.
Graphical abstractDownload full-size image
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Bojan Burja, Marijan KoÄevar, Slovenko Polanc,