| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5222262 | Tetrahedron | 2011 | 6 Pages |
Abstract
We have discovered a series of N-bromosuccinimide-promoted 1,4-bromocyclization reactions for conjugated 1,3-enynes. Various nitrogen nucleophiles could be added to conjugated enynes to generate bromoallenyl substituted nitrogen heterocycles. These processes led to simultaneous formation of a highly functionalized axially chiral allene and a stereogenic center under mild conditions.
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Physical Sciences and Engineering
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Organic Chemistry
