| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5222271 | Tetrahedron | 2011 | 7 Pages |
Abstract
We have discovered a photocatalytic intramolecular hetero-Diels–Alder reaction of tethered bis(enones). This transformation involves the intermediacy of an enone radical anion and constitutes the formal coupling of an electron-deficient heterodiene with an electronically mismatched enone dienophile. The diastereoselectivity and regioselectivity of the process are high, and the dihydropyran products are amenable to a variety of synthetically useful transformations.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
