| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5222371 | Tetrahedron | 2011 | 4 Pages |
Abstract
An AE azabicyclic fragment, with a β-hydroxyl group at C-5 and a substituent at C-1, of the C19-diterpenoid alkaloids, was synthesized. The key reactions include an intramolecular Claisen-type condensation, double Mannich reaction, and stereoselective nucleophilic addition of carbonyl group with the assistance of steric effect of 1β-substituent.
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