Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222479 | Tetrahedron | 2009 | 6 Pages |
Abstract
A series of chiral bifunctional phosphinothioureas were synthesized and applied to the enantioselective Morita-Baylis-Hillman reaction of aromatic aldehydes with acrylates. In the presence of 8 mol % of organocatalyst 2e, the Baylis-Hillman adducts were obtained in good enantioselectivities and up to 96% yield under mild reaction conditions.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kui Yuan, Hong-Liang Song, Yinjun Hu, Xin-Yan Wu,