| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5222512 | Tetrahedron | 2011 | 8 Pages |
Abstract
An efficient direct amination of quinazolin-4(3H)-ones has been developed. Treatment of quinazolin-4(3H)-ones with HCCP, DIPEA, and N-contained nucleophiles in acetonitrile could be able to form the corresponding 4-aminoquinazoline derivatives. Under the optimal reaction conditions, the amination products were achieved in good yields.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zhenlu Shen, Xiaofei He, Jialiang Dai, Weimin Mo, Baoxiang Hu, Nan Sun, Xinquan Hu,