Article ID Journal Published Year Pages File Type
5222539 Tetrahedron 2011 6 Pages PDF
Abstract

The Biginelli 3,4-dihydropyrimidin-2(1H)-one was converted to various C2-multifunctionalized pyrimidines via the dehydrogenation and Mitsunobu reaction using amines, alcohols, phenols and carboxylic acids as nucleophiles. A possible mechanism was also proposed to rationalize the formation of products.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry