Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222567 | Tetrahedron | 2009 | 7 Pages |
Abstract
Catalytic asymmetric vinylogous Mannich (AVM) reactions of readily available aldimines with trimethylsiloxyfuran in the presence of catalytic amount of AgOAc and chiral phosphine-Schiff base type ligands are described, affording the corresponding products in up to 91% yield, anti/syn >99:1 and 81% ee.
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