Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222573 | Tetrahedron | 2009 | 8 Pages |
Abstract
A series of ribonucleoside 1-alkynylphosphonates have been synthesized using a palladium-catalyzed phosphonylation of terminal 1,1-dibromo-1-alkene nucleosidic derivatives and high selectivity for product distribution was observed during this step. Both nucleosidic and osidic pathways were explored and the corresponding optimization study is reported herein.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Maïa Meurillon, Franck Gallier, Suzanne Peyrottes, Christian Périgaud,