Article ID Journal Published Year Pages File Type
5222573 Tetrahedron 2009 8 Pages PDF
Abstract

A series of ribonucleoside 1-alkynylphosphonates have been synthesized using a palladium-catalyzed phosphonylation of terminal 1,1-dibromo-1-alkene nucleosidic derivatives and high selectivity for product distribution was observed during this step. Both nucleosidic and osidic pathways were explored and the corresponding optimization study is reported herein.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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