Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222651 | Tetrahedron | 2009 | 8 Pages |
Abstract
A stereoselective synthesis of the C13-C25 of Calyculin C is described. Key steps involve the coupling of a terminal acetylene with a thiol ester and subsequent spirocyclisation using a double intramolecular hetero-Michael addition.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Damien Habrant, Alan J.W. Stewart, Ari M.P. Koskinen,