Article ID Journal Published Year Pages File Type
5222651 Tetrahedron 2009 8 Pages PDF
Abstract

A stereoselective synthesis of the C13-C25 of Calyculin C is described. Key steps involve the coupling of a terminal acetylene with a thiol ester and subsequent spirocyclisation using a double intramolecular hetero-Michael addition.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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