Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222663 | Tetrahedron | 2009 | 7 Pages |
Abstract
Hydrophobically tagged prolyl peptides were synthesized using an electrochemically modified prolyl moiety. The hydrophobic tag served a useful handle for the repetitive reaction/separation steps during solution-phase peptide synthesis. Furthermore, the tag was also effective as an anchor on solid phases for the evaluation of activity of immobilized peptides.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kazuhiro Chiba, Mari Sugihara, Kazumi Yoshida, Yuzuru Mikami, Shokaku Kim,