Article ID Journal Published Year Pages File Type
5222704 Tetrahedron 2011 9 Pages PDF
Abstract

Six new aziridine-containing analogs of phytosphingosine designed as constrained anhydrophytosphingosine were synthesized. The synthetic route developed also afforded an access to an original bicyclic analog of the natural anhydrophytosphingosine jaspine B. All these new compounds were evaluated for their capacities to affect melanoma cell viability.

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry