Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222717 | Tetrahedron | 2011 | 6 Pages |
Abstract
Very high regioselective 1,2-addition of organolithiums to α,β-unsaturated carbonyl-like compounds (ketones, aldehydes, and imines) in the presence of LiBr was achieved by carrying out reactions in the sustainable solvent 2-methyltetrahydrofuran. Excellent yields (in isolated product) of allylic alcohols and allylic amines were recovered under a simple experimental procedure at 0 °C.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Vittorio Pace, Laura Castoldi, Pilar Hoyos, José Vicente Sinisterra, Massimo Pregnolato, José Ma Sánchez-Montero,