Article ID Journal Published Year Pages File Type
5222717 Tetrahedron 2011 6 Pages PDF
Abstract

Very high regioselective 1,2-addition of organolithiums to α,β-unsaturated carbonyl-like compounds (ketones, aldehydes, and imines) in the presence of LiBr was achieved by carrying out reactions in the sustainable solvent 2-methyltetrahydrofuran. Excellent yields (in isolated product) of allylic alcohols and allylic amines were recovered under a simple experimental procedure at 0 °C.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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