| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5222745 | Tetrahedron | 2009 | 4 Pages |
Abstract
A regioselective coupling of ethyl 2-(bromomethyl)-3-cyanoacrylate and primary amines is described to give ethyl 2-[(alkylamino)(cyano)methyl] acrylates in good yields. Whereas the conversion of allyl bromide in the presence of TEAF leads to the first synthesis of ethyl 3-cyano-2-(hydroxymethyl) acrylate.
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Physical Sciences and Engineering
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Organic Chemistry
![An effective new access to ethyl 2-[(alkylamino)(cyano)methyl] acrylates: first synthesis of ethyl 3-cyano-2-(hydroxymethyl) acrylate](/preview/png/5222745.png "First Page Preview: An effective new access to ethyl 2-[(alkylamino)(cyano)methyl] acrylates: first synthesis of ethyl 3-cyano-2-(hydroxymethyl) acrylate")
Authors
Aïcha Arfaoui, Hassen Amri,