Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222779 | Tetrahedron | 2010 | 7 Pages |
Abstract
This paper describes a simple and efficient one-pot synthetic approach for the preparation of biologically interesting 3,4-dihydroquinoxalin-2-amine derivatives using EDTA-catalyzed three-component reactions of o-phenylenediamines, carbonyl compounds, and isocyanides in an aqueous medium. This method is of great value because of its environmentally benign character, high yields, and ease of handling.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Srinivasa Rao Kolla, Yong Rok Lee,