| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5222815 | Tetrahedron | 2009 | 15 Pages |
Abstract
The safe and reliable use of various fluorination methods including nucleophilic fluorination (DAST), trifluoromethylation (Ruppert's reagent) and electrophilic fluorination (Selectfluor®) in a continuous-flow microreactor is reported. Special attention was given to the use of in-line scavenging procedures in order to obtain clean products without the need for further purification.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Marcus Baumann, Ian R. Baxendale, Laetitia J. Martin, Steven V. Ley,