| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5222819 | Tetrahedron | 2009 | 8 Pages |
Abstract
This report describes a number of new synthetic approaches toward methyl-substituted mono- and diepoxy alcohols that serve as substrates for endo-selective epoxide-opening cascades. The key transformations involve the manipulation of alkynes. Highlighted are the directed methylmetalation of bishomopropargylic alcohols, the bromoallylation of alkynes, and Pd-catalyzed cross-coupling between an alkenyl boronate ester and allylic bromides.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Christopher J. Morten, Timothy F. Jamison,