Article ID Journal Published Year Pages File Type
5222866 Tetrahedron 2011 6 Pages PDF
Abstract

N-Alkoxymethylation of heterocyclic compounds with diethyl phosphite via cleavage of P–O bond was investigated and a series of N3-ethoxymethylated heterocyclic compounds were synthesized. A mechanism in which diethyl phosphite acts as an efficient surrogate of ethanol was proposed and supported by several evidences.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry